| First | Last | Nickname | Ht. | Wt. | Reach | Stance | W | L | D | Belt |
|---|---|---|---|---|---|---|---|---|---|---|
| Leon | Shahbazyan | 6' 4" | 170 lbs. | 74.0" | Orthodox | 7 | 2 | 0 | ||
| Don | Shainis | Shameless | 5' 6" | 145 lbs. | 67.0" | Orthodox | 12 | 5 | 0 | |
| Liliya | Shakirova | 5' 4" | 125 lbs. | 65.0" | Orthodox | 8 | 2 | 0 | ||
| Kamal | Shalorus | Prince of Persia | 5' 8" | 155 lbs. | 68.0" | Orthodox | 9 | 5 | 2 | |
| Ken | Shamrock | The World's Most Dangerous Man | 6' 1" | 205 lbs. | 72.0" | Orthodox | 28 | 17 | 2 | |
| Frank | Shamrock | 5' 10" | 185 lbs. | -- | Orthodox | 23 | 10 | 2 | ||
| Shang | Zhifa | Northeast Flying Tiger | 5' 7" | 125 lbs. | 63.0" | Orthodox | 32 | 8 | 0 | |
| Priya | Sharma | -- | 115 lbs. | -- | 5 | 1 | 0 | |||
| Jason | Sharp | -- | 205 lbs. | -- | 3 | 3 | 0 | |||
| Eric | Shelton | Showtime | 5' 6" | 125 lbs. | 68.0" | Orthodox | 12 | 6 | 0 | |
| Sean | Sherk | The Muscle Shark | 5' 6" | 155 lbs. | 67.0" | Orthodox | 36 | 4 | 1 | |
| Chase | Sherman | The Vanilla Gorilla | 6' 4" | 250 lbs. | 78.0" | Orthodox | 16 | 12 | 0 | |
| Valentina | Shevchenko | Bullet | 5' 5" | 125 lbs. | 66.0" | Southpaw | 23 | 4 | 1 | |
| Antonina | Shevchenko | La Pantera | 5' 8" | 125 lbs. | 67.0" | Southpaw | 10 | 4 | 0 | |
| Ming | Shi | -- | 115 lbs. | -- | 14 | 5 | 0 | |||
| Katsuyori | Shibata | 6' 0" | 168 lbs. | -- | Orthodox | 4 | 11 | 1 | ||
| Jake | Shields | 6' 0" | 170 lbs. | 72.0" | Orthodox | 31 | 9 | 1 | ||
| Henrique | Shiguemoto | 5' 11" | 185 lbs. | 72.0" | Orthodox | 13 | 4 | 1 | ||
| Shunichi | Shimizu | 5' 5" | 135 lbs. | -- | Orthodox | 30 | 18 | 11 | ||
| Wade | Shipp | The Nightmare | 6' 3" | 245 lbs. | -- | Orthodox | 11 | 5 | 0 | |
| Raja | Shippen | 5' 6" | 145 lbs. | -- | 18 | 11 | 1 | |||
| Yuya | Shirai | 5' 8" | 168 lbs. | -- | Orthodox | 26 | 14 | 2 | ||
| Wes | Shivers | 6' 8" | -- | -- | 7 | 1 | 0 | |||
| Alexander | Shlemenko | Storm | 5' 11" | 185 lbs. | -- | 56 | 9 | 0 |